High Quality Guaranteen Anti-Hair Loss 99% CB-03-01/Clascoterone CAS 19608-29-8 to Restore Hair and Combat Pattern Baldness
Product name |
CB-03-01 |
CAS number |
19608-29-8 |
Purity |
>99% |
Transport Package |
1kg/Drum or Customized |
Appearance |
White Powder |
Storage |
After reconstitution store at 2 ºC- 8ºC |
Cortexolone 17α-propionate (developmental code name CB-03-01), or 11-deoxycortisol 17α-propionate, is a synthetic steroidal antiandrogen-specifically, an androgen receptor antagonist - which is used as a topical medication in the treatment of androgen-dependent conditions including acne vulgaris and androgenic alopecia (male-pattern hair loss). It is the C17α propionate ester of 11-deoxycortisol (cortexolone); C17α esters of 11-deoxycortisol were unexpectedly found to possess antiandrogen activity, and cortexolone 17α-propionate was selected for development based on its optimum drug profile.
Function:
CB-03-01 is the drug for the treatment of hair loss dwindled. It has same function and application with RU58841 and Setipiprant.
Application:
CB-03-01 is a molecule that acts at the level of the skin, blocking (DHT) from binding to the receptor in the cell. The molecule has a unique mechanism that acts at the skin surface, and is quickly metabolized to free inactive cortexolone, a substance naturally found in the body. The molecule has been evaluated in a variety of animal models as well as initial human trials in Europe. The results of these studies demonstrate that CB-03-01 appears to have potent activity without significant local or systemic side effects.
Density |
1.2±0.1 g/cm3 |
Boiling Point |
538.9±50.0 °C at 760 mmHg |
Molecular Formula |
C24H34O5 |
Molecular Weight |
402.524 |
Flash Point |
179.3±23.6 °C |
Exact Mass |
402.240631 |
PSA |
80.67000 |
LogP |
3.76 |
Vapour Pressure |
0.0±3.3 mmHg at 25°C |
Index of Refraction |
1.555 |
Zhengzhou Qizheng Trading Co., Ltd. mainly produces medical intermediates, chemical raw materials, biological products and other series, is a collection of development, production, domestic and foreign trade sales as one of the large-scale fine chemical raw materials production enterprises. We stick to the principle of "quality first, service first, continuous improvement and innovation to meet the customers" for the management and "zero defect, zero complaints" as the quality objective.
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